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2021-06-15

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2021-06-10

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2021-06-10

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U.S. stocks end lower ahead of inflation report

2021-06-08

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2021-06-08

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Biogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK

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and comment pls","listText":"Like and comment pls","text":"Like and comment pls","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":2,"repostSize":0,"link":"https://ttm.financial/post/187674824","repostId":"1142697857","repostType":4,"isVote":1,"tweetType":1,"viewCount":1292,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":189543286,"gmtCreate":1623283148145,"gmtModify":1704199912054,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3579400009595208","idStr":"3579400009595208"},"themes":[],"htmlText":"??","listText":"??","text":"??","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/189543286","repostId":"2142938243","repostType":4,"isVote":1,"tweetType":1,"viewCount":1043,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":189540058,"gmtCreate":1623283060874,"gmtModify":1704199908943,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3579400009595208","idStr":"3579400009595208"},"themes":[],"htmlText":"Pls like and comment ?","listText":"Pls like and comment ?","text":"Pls like and comment ?","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":2,"repostSize":0,"link":"https://ttm.financial/post/189540058","repostId":"1142408805","repostType":4,"repost":{"id":"1142408805","kind":"news","pubTimestamp":1623280126,"share":"https://ttm.financial/m/news/1142408805?lang=en_US&edition=fundamental","pubTime":"2021-06-10 07:08","market":"us","language":"en","title":"U.S. stocks end lower ahead of inflation report","url":"https://stock-news.laohu8.com/highlight/detail?id=1142408805","media":"reuters","summary":"NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants a","content":"<p>NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants awaited inflation data for clues as to when the U.S. Federal Reserve might tighten its dovish monetary policy.</p>\n<p>The retail “meme stock” craze continued unabated.</p>\n<p>All three major U.S. stock indexes reversed earlier gains, but remained range-bound in the absence of any clear market catalysts.</p>\n<p>“There’s a lull period in terms of news,” said Chuck Carlson, chief executive at Horizon Investment Services in Hammond, Indiana. “We’re through earnings period and people are waiting for inflation numbers tomorrow, so you have a mixed market where the major averages aren’t doing much of anything.”</p>\n<p>Heavily shorted meme stocks extended their social media-driven rally, with Aethlon Medical soaring 388.2%.</p>\n<p>Reddit chatter also helped to lift shares of prison operator GEO Group and World Wrestling Entertainment 38.4% and 10.9%, respectively.</p>\n<p>However, other meme stocks such as Clover Health, AMC Entertainment and Bed Bath &amp; Beyond closed lower.</p>\n<p>Retail volume has returned to its January peak, according to Vanda Research, as social media forums scramble to identify the next GameStop Corp, the stock that kicked off the phenomenon.</p>\n<p>“It feels like alternative stock market,” Carlson added. It’s an indication of speculation. You can be successful if you get in at the right moment but it’s very difficult to play successfully over time.”</p>\n<p>“I don’t think you should read too much regarding the broader market.”</p>\n<p>GameStop named Matt Furlong as its new CEO ahead of its earnings report, which showed a quarterly loss of $1.01 per share. Its shares fell over 4% in after-hours trading.</p>\n<p>U.S. President Joe Biden changed course in ongoing negotiations to reach a bipartisan agreement on infrastructure spending after one-on-one talks with Senator Shelley Capito broke down.</p>\n<p>Industrial stocks, which stand to benefit from an infrastructure deal, slid by 1%.</p>\n<p>Washington lawmakers passed a sweeping bill designed to boost the United States’ ability to compete against Chinese technology, providing funds for research and semiconductor production amid an ongoing chip supply drought. The bill now heads to the House of Representatives.</p>\n<p>Even so, the Philadelphia SE Semiconductor index slipped 0.4%.</p>\n<p>The Labor Department’s consumer price index report due out Thursday will provide another take on inflation amid the recovery’s demand/supply imbalance as investors determine whether inflationary pressures, as the Fed asserts, will be transitory.</p>\n<p>The Dow Jones Industrial Average fell 152.68 points, or 0.44%, to 34,447.14; the S&amp;P 500 lost 7.71 points, or 0.18%, at 4,219.55; and the Nasdaq Composite dropped 13.16 points, or 0.09%, to 13,911.75.</p>\n<p>Among the 11 major sectors in the S&amp;P 500, healthcare gained the most.</p>\n<p>Benchmark Treasury yields dropped below 1.5% for the first time since May, weighing on interest-sensitive financials.</p>\n<p>Campbell Soup Co missed quarterly profit expectations and slashed its full-year earnings forecast, sending its shares down 6.5%.</p>\n<p>Drugmaker Merck &amp; Co rose 2.3% on the heels of its announcement the U.S. government had agreed to buy about 1.7 million courses of the company’s experimental COVID-19 treatment, molnupiravir, for about $1.2 billion, if the drug meets regulatory approval.</p>\n<p>Declining issues outnumbered advancers on the NYSE by a 1.12-to-1 ratio; on Nasdaq, a 1.13-to-1 ratio favored decliners.</p>\n<p>The S&amp;P 500 posted 38 new 52-week highs and two new lows; the Nasdaq Composite recorded 126 new highs and 14 new lows.</p>\n<p>Volume on U.S. exchanges was 11.53 billion shares, compared with the 10.74 billion average over the last 20 trading days.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>U.S. stocks end lower ahead of inflation report</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nU.S. stocks end lower ahead of inflation report\n</h2>\n\n<h4 class=\"meta\">\n\n\n2021-06-10 07:08 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://www.reuters.com/article/usa-stocks/us-stocks-u-s-stocks-end-lower-ahead-of-inflation-report-idUSL2N2NR2UG><strong>reuters</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants awaited inflation data for clues as to when the U.S. Federal Reserve might tighten its dovish ...</p>\n\n<a href=\"https://www.reuters.com/article/usa-stocks/us-stocks-u-s-stocks-end-lower-ahead-of-inflation-report-idUSL2N2NR2UG\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"AEMD":"Aethlon Medical Inc",".SPX":"S&P 500 Index",".DJI":"道琼斯",".IXIC":"NASDAQ Composite"},"source_url":"https://www.reuters.com/article/usa-stocks/us-stocks-u-s-stocks-end-lower-ahead-of-inflation-report-idUSL2N2NR2UG","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1142408805","content_text":"NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants awaited inflation data for clues as to when the U.S. Federal Reserve might tighten its dovish monetary policy.\nThe retail “meme stock” craze continued unabated.\nAll three major U.S. stock indexes reversed earlier gains, but remained range-bound in the absence of any clear market catalysts.\n“There’s a lull period in terms of news,” said Chuck Carlson, chief executive at Horizon Investment Services in Hammond, Indiana. “We’re through earnings period and people are waiting for inflation numbers tomorrow, so you have a mixed market where the major averages aren’t doing much of anything.”\nHeavily shorted meme stocks extended their social media-driven rally, with Aethlon Medical soaring 388.2%.\nReddit chatter also helped to lift shares of prison operator GEO Group and World Wrestling Entertainment 38.4% and 10.9%, respectively.\nHowever, other meme stocks such as Clover Health, AMC Entertainment and Bed Bath & Beyond closed lower.\nRetail volume has returned to its January peak, according to Vanda Research, as social media forums scramble to identify the next GameStop Corp, the stock that kicked off the phenomenon.\n“It feels like alternative stock market,” Carlson added. It’s an indication of speculation. You can be successful if you get in at the right moment but it’s very difficult to play successfully over time.”\n“I don’t think you should read too much regarding the broader market.”\nGameStop named Matt Furlong as its new CEO ahead of its earnings report, which showed a quarterly loss of $1.01 per share. Its shares fell over 4% in after-hours trading.\nU.S. President Joe Biden changed course in ongoing negotiations to reach a bipartisan agreement on infrastructure spending after one-on-one talks with Senator Shelley Capito broke down.\nIndustrial stocks, which stand to benefit from an infrastructure deal, slid by 1%.\nWashington lawmakers passed a sweeping bill designed to boost the United States’ ability to compete against Chinese technology, providing funds for research and semiconductor production amid an ongoing chip supply drought. The bill now heads to the House of Representatives.\nEven so, the Philadelphia SE Semiconductor index slipped 0.4%.\nThe Labor Department’s consumer price index report due out Thursday will provide another take on inflation amid the recovery’s demand/supply imbalance as investors determine whether inflationary pressures, as the Fed asserts, will be transitory.\nThe Dow Jones Industrial Average fell 152.68 points, or 0.44%, to 34,447.14; the S&P 500 lost 7.71 points, or 0.18%, at 4,219.55; and the Nasdaq Composite dropped 13.16 points, or 0.09%, to 13,911.75.\nAmong the 11 major sectors in the S&P 500, healthcare gained the most.\nBenchmark Treasury yields dropped below 1.5% for the first time since May, weighing on interest-sensitive financials.\nCampbell Soup Co missed quarterly profit expectations and slashed its full-year earnings forecast, sending its shares down 6.5%.\nDrugmaker Merck & Co rose 2.3% on the heels of its announcement the U.S. government had agreed to buy about 1.7 million courses of the company’s experimental COVID-19 treatment, molnupiravir, for about $1.2 billion, if the drug meets regulatory approval.\nDeclining issues outnumbered advancers on the NYSE by a 1.12-to-1 ratio; on Nasdaq, a 1.13-to-1 ratio favored decliners.\nThe S&P 500 posted 38 new 52-week highs and two new lows; the Nasdaq Composite recorded 126 new highs and 14 new lows.\nVolume on U.S. exchanges was 11.53 billion shares, compared with the 10.74 billion average over the last 20 trading days.","news_type":1,"symbols_score_info":{".SPX":0.9,".IXIC":0.9,".DJI":0.9,"AEMD":0.9}},"isVote":1,"tweetType":1,"viewCount":1840,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":117163297,"gmtCreate":1623123282119,"gmtModify":1704196561131,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3579400009595208","idStr":"3579400009595208"},"themes":[],"htmlText":"Comment pls!","listText":"Comment pls!","text":"Comment pls!","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":4,"repostSize":0,"link":"https://ttm.financial/post/117163297","repostId":"2141342255","repostType":4,"isVote":1,"tweetType":1,"viewCount":1665,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":117169226,"gmtCreate":1623123180365,"gmtModify":1704196559664,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3579400009595208","idStr":"3579400009595208"},"themes":[],"htmlText":"Happy to read this news","listText":"Happy to read this news","text":"Happy to read this news","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/117169226","repostId":"2141453253","repostType":4,"repost":{"id":"2141453253","kind":"highlight","weMediaInfo":{"introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"media_name":"Dow Jones","id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"pubTimestamp":1623096780,"share":"https://ttm.financial/m/news/2141453253?lang=en_US&edition=fundamental","pubTime":"2021-06-08 04:13","market":"us","language":"en","title":"Biogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK","url":"https://stock-news.laohu8.com/highlight/detail?id=2141453253","media":"Dow Jones","summary":"Shares rally to second -biggest one-day percentage gain since they went public 30 years agoShares of","content":"<p>Shares rally to second -biggest <a href=\"https://laohu8.com/S/AONE\">one</a>-day percentage gain since they went public 30 years ago</p><p>Shares of Biogen Inc. rocketed to a six-year high in volatile trading Monday, as Wall Street analysts cheered the U.S. Food and Drug Administration's broad labeling that came with the approval of the biotechnology company's Alzheimer's drug.</p><p>The stock <a href=\"https://laohu8.com/S/BIIB\">$(BIIB)$</a> blasted $109.71, or 38.3% higher, to $395.85, the highest close since April 2015. The stock had been halted twice for volatility  during Monday's session, once at 10:44 a.m. Eastern and a second time at 1:37 p.m.</p><p>Trading volume spiked up to 17.7 million shares, compared with the full-day average over the past 30 days of about 1.0 million shares, according to FactSet.</p><p>Earlier Friday, the FDA approved Biogen's Aduhelm , also known as aducanumab, to treat Alzheimer's, the first drug to be approved that promises to actually slow the disease rather than just treat the symptoms.</p><p>Biogen investors were treated to the stock's biggest-ever <a href=\"https://laohu8.com/S/AONE.U\">one</a>-day price gain, and second-biggest one-day percentage gain since it went public in September 1991. The stock had shot up $108.62, or 44.0%, on Nov. 4, 2020, after the FDA said there was \"substantial evidence\"</p><p>\"Currently available options only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer's,\" said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research. \"As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research an innovation.\"</p><p>As the FDA described, accelerated approval can be based on the drug's effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients, with \"a required post-approval trial\" to verify the drug provides that expected clinical benefit.</p><p>Bernstein analyst Aaron Gal said approval under accelerated pathway is a distinction without a difference. \"The pathway allows for approval based on surrogate market, rather than completed efficacy endpoint data,\" Gal wrote in a note to clients. \"As long as Biogen does not challenge the use of the path, which they obviously would not, the approval holds.\"</p><p>Evercore ISI's Umer Raffat noted that the option of Accelerated Approval was not discussed by the FDA's advisory committee. And as the drug has \"clearly shown\" in all trials to substantially reduce amyloid beta plaques, the \"reduction in plaques is reasonably likely to result in clinical benefit.\"</p><p>Regarding labeling, Bernstein's Gal said it is \"almost shockingly broad,\" as the label just said Aduhelm is indicated for the treatment of Alzheimer's disease.</p><p>\"Thus, the approved population is broader than the tested population (mild-moderate Alzheimer's patients),\" Gal wrote. \"There is also no restriction on treatment duration suggesting that patients can stay on treatment until either all plaque is removed or the patient progresses.\"</p><p>Evercore's Raffat concurred, saying the label reads very very broad. He indicated that investors could be relieved, as there was some concern that the target population might be limited, and/or require very frequent monitoring.</p><p>Although pricing is still unknown, the Institute of Clinical and Economic Review (ICER) said that due to the relatively small overall health gains demonstrated in Phase 3 clinical trials, the drug should be price no higher than $8,400 a year, as MarketWatch's Jaimy Lee reported .</p><p>Some analysts say Biogen could price the drug higher than that, even though that might potentially trigger a regulatory response.</p><p>Evercore's Raffat said his financial estimates on Biogen include an estimate of $10,000, while Bernstein's Gal said the pricing could end up \"much higher,\" possibly as high as more than $30,000.</p><p>Gal said Biogen has a long history of pricing drugs in the \"specialty\" range, and is less likely to fear a backlash. \"Biogen would justify the price by arguing the total system impact would be modest upfront and that it will use the money to provide substantial services to [Alzheimer's disease] patients,\" Gal wrote.</p><p>Biogen and Eisai Inc., the U.S. subsidiary of Japan-based Eisai Co. Ltd. (4523.TO), announced after Aduhelm's approval programs intended to support access for all qualified patients, including those from traditionally underserved populations.</p><p>Eisai's U.S.-listed shares skyrocketed 68.9% in afternoon trading, on track for a record close and the biggest one-day gain since it started trading in the U.S. in December 1995.</p><p>\"We are committed to access and health equity as top priorities and will continue working with multiple stakeholders with the goal of helping patients who may benefit from treatment obtain care as quickly as possible,\" said Alisha Alaimo, president of Biogen U.S.</p><p>Biogen's stock has now run up 61.7% year to date, while SPDR Health Care Select Sector exchange-traded fund <a href=\"https://laohu8.com/S/XLV\">$(XLV)$</a> has gained 8.0% and the S&amp;P 500 index  has advanced 12.5%.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Biogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nBiogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK\n</h2>\n\n<h4 class=\"meta\">\n\n\n<div class=\"head\" \">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Dow Jones </p>\n<p class=\"h-time\">2021-06-08 04:13</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<p>Shares rally to second -biggest <a href=\"https://laohu8.com/S/AONE\">one</a>-day percentage gain since they went public 30 years ago</p><p>Shares of Biogen Inc. rocketed to a six-year high in volatile trading Monday, as Wall Street analysts cheered the U.S. Food and Drug Administration's broad labeling that came with the approval of the biotechnology company's Alzheimer's drug.</p><p>The stock <a href=\"https://laohu8.com/S/BIIB\">$(BIIB)$</a> blasted $109.71, or 38.3% higher, to $395.85, the highest close since April 2015. The stock had been halted twice for volatility  during Monday's session, once at 10:44 a.m. Eastern and a second time at 1:37 p.m.</p><p>Trading volume spiked up to 17.7 million shares, compared with the full-day average over the past 30 days of about 1.0 million shares, according to FactSet.</p><p>Earlier Friday, the FDA approved Biogen's Aduhelm , also known as aducanumab, to treat Alzheimer's, the first drug to be approved that promises to actually slow the disease rather than just treat the symptoms.</p><p>Biogen investors were treated to the stock's biggest-ever <a href=\"https://laohu8.com/S/AONE.U\">one</a>-day price gain, and second-biggest one-day percentage gain since it went public in September 1991. The stock had shot up $108.62, or 44.0%, on Nov. 4, 2020, after the FDA said there was \"substantial evidence\"</p><p>\"Currently available options only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer's,\" said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research. \"As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research an innovation.\"</p><p>As the FDA described, accelerated approval can be based on the drug's effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients, with \"a required post-approval trial\" to verify the drug provides that expected clinical benefit.</p><p>Bernstein analyst Aaron Gal said approval under accelerated pathway is a distinction without a difference. \"The pathway allows for approval based on surrogate market, rather than completed efficacy endpoint data,\" Gal wrote in a note to clients. \"As long as Biogen does not challenge the use of the path, which they obviously would not, the approval holds.\"</p><p>Evercore ISI's Umer Raffat noted that the option of Accelerated Approval was not discussed by the FDA's advisory committee. And as the drug has \"clearly shown\" in all trials to substantially reduce amyloid beta plaques, the \"reduction in plaques is reasonably likely to result in clinical benefit.\"</p><p>Regarding labeling, Bernstein's Gal said it is \"almost shockingly broad,\" as the label just said Aduhelm is indicated for the treatment of Alzheimer's disease.</p><p>\"Thus, the approved population is broader than the tested population (mild-moderate Alzheimer's patients),\" Gal wrote. \"There is also no restriction on treatment duration suggesting that patients can stay on treatment until either all plaque is removed or the patient progresses.\"</p><p>Evercore's Raffat concurred, saying the label reads very very broad. He indicated that investors could be relieved, as there was some concern that the target population might be limited, and/or require very frequent monitoring.</p><p>Although pricing is still unknown, the Institute of Clinical and Economic Review (ICER) said that due to the relatively small overall health gains demonstrated in Phase 3 clinical trials, the drug should be price no higher than $8,400 a year, as MarketWatch's Jaimy Lee reported .</p><p>Some analysts say Biogen could price the drug higher than that, even though that might potentially trigger a regulatory response.</p><p>Evercore's Raffat said his financial estimates on Biogen include an estimate of $10,000, while Bernstein's Gal said the pricing could end up \"much higher,\" possibly as high as more than $30,000.</p><p>Gal said Biogen has a long history of pricing drugs in the \"specialty\" range, and is less likely to fear a backlash. \"Biogen would justify the price by arguing the total system impact would be modest upfront and that it will use the money to provide substantial services to [Alzheimer's disease] patients,\" Gal wrote.</p><p>Biogen and Eisai Inc., the U.S. subsidiary of Japan-based Eisai Co. Ltd. (4523.TO), announced after Aduhelm's approval programs intended to support access for all qualified patients, including those from traditionally underserved populations.</p><p>Eisai's U.S.-listed shares skyrocketed 68.9% in afternoon trading, on track for a record close and the biggest one-day gain since it started trading in the U.S. in December 1995.</p><p>\"We are committed to access and health equity as top priorities and will continue working with multiple stakeholders with the goal of helping patients who may benefit from treatment obtain care as quickly as possible,\" said Alisha Alaimo, president of Biogen U.S.</p><p>Biogen's stock has now run up 61.7% year to date, while SPDR Health Care Select Sector exchange-traded fund <a href=\"https://laohu8.com/S/XLV\">$(XLV)$</a> has gained 8.0% and the S&amp;P 500 index  has advanced 12.5%.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"BIIB":"渤健公司"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2141453253","content_text":"Shares rally to second -biggest one-day percentage gain since they went public 30 years agoShares of Biogen Inc. rocketed to a six-year high in volatile trading Monday, as Wall Street analysts cheered the U.S. Food and Drug Administration's broad labeling that came with the approval of the biotechnology company's Alzheimer's drug.The stock $(BIIB)$ blasted $109.71, or 38.3% higher, to $395.85, the highest close since April 2015. The stock had been halted twice for volatility  during Monday's session, once at 10:44 a.m. Eastern and a second time at 1:37 p.m.Trading volume spiked up to 17.7 million shares, compared with the full-day average over the past 30 days of about 1.0 million shares, according to FactSet.Earlier Friday, the FDA approved Biogen's Aduhelm , also known as aducanumab, to treat Alzheimer's, the first drug to be approved that promises to actually slow the disease rather than just treat the symptoms.Biogen investors were treated to the stock's biggest-ever one-day price gain, and second-biggest one-day percentage gain since it went public in September 1991. The stock had shot up $108.62, or 44.0%, on Nov. 4, 2020, after the FDA said there was \"substantial evidence\"\"Currently available options only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer's,\" said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research. \"As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research an innovation.\"As the FDA described, accelerated approval can be based on the drug's effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients, with \"a required post-approval trial\" to verify the drug provides that expected clinical benefit.Bernstein analyst Aaron Gal said approval under accelerated pathway is a distinction without a difference. \"The pathway allows for approval based on surrogate market, rather than completed efficacy endpoint data,\" Gal wrote in a note to clients. \"As long as Biogen does not challenge the use of the path, which they obviously would not, the approval holds.\"Evercore ISI's Umer Raffat noted that the option of Accelerated Approval was not discussed by the FDA's advisory committee. And as the drug has \"clearly shown\" in all trials to substantially reduce amyloid beta plaques, the \"reduction in plaques is reasonably likely to result in clinical benefit.\"Regarding labeling, Bernstein's Gal said it is \"almost shockingly broad,\" as the label just said Aduhelm is indicated for the treatment of Alzheimer's disease.\"Thus, the approved population is broader than the tested population (mild-moderate Alzheimer's patients),\" Gal wrote. \"There is also no restriction on treatment duration suggesting that patients can stay on treatment until either all plaque is removed or the patient progresses.\"Evercore's Raffat concurred, saying the label reads very very broad. He indicated that investors could be relieved, as there was some concern that the target population might be limited, and/or require very frequent monitoring.Although pricing is still unknown, the Institute of Clinical and Economic Review (ICER) said that due to the relatively small overall health gains demonstrated in Phase 3 clinical trials, the drug should be price no higher than $8,400 a year, as MarketWatch's Jaimy Lee reported .Some analysts say Biogen could price the drug higher than that, even though that might potentially trigger a regulatory response.Evercore's Raffat said his financial estimates on Biogen include an estimate of $10,000, while Bernstein's Gal said the pricing could end up \"much higher,\" possibly as high as more than $30,000.Gal said Biogen has a long history of pricing drugs in the \"specialty\" range, and is less likely to fear a backlash. \"Biogen would justify the price by arguing the total system impact would be modest upfront and that it will use the money to provide substantial services to [Alzheimer's disease] patients,\" Gal wrote.Biogen and Eisai Inc., the U.S. subsidiary of Japan-based Eisai Co. Ltd. (4523.TO), announced after Aduhelm's approval programs intended to support access for all qualified patients, including those from traditionally underserved populations.Eisai's U.S.-listed shares skyrocketed 68.9% in afternoon trading, on track for a record close and the biggest one-day gain since it started trading in the U.S. in December 1995.\"We are committed to access and health equity as top priorities and will continue working with multiple stakeholders with the goal of helping patients who may benefit from treatment obtain care as quickly as possible,\" said Alisha Alaimo, president of Biogen U.S.Biogen's stock has now run up 61.7% year to date, while SPDR Health Care Select Sector exchange-traded fund $(XLV)$ has gained 8.0% and the S&P 500 index  has advanced 12.5%.","news_type":1,"symbols_score_info":{"ESALY":0.9,"BIIB":0.9}},"isVote":1,"tweetType":1,"viewCount":1263,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"hots":[{"id":117163297,"gmtCreate":1623123282119,"gmtModify":1704196561131,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3579400009595208","authorIdStr":"3579400009595208"},"themes":[],"htmlText":"Comment pls!","listText":"Comment pls!","text":"Comment pls!","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":4,"repostSize":0,"link":"https://ttm.financial/post/117163297","repostId":"2141342255","repostType":4,"isVote":1,"tweetType":1,"viewCount":1665,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":189540058,"gmtCreate":1623283060874,"gmtModify":1704199908943,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3579400009595208","authorIdStr":"3579400009595208"},"themes":[],"htmlText":"Pls like and comment ?","listText":"Pls like and comment ?","text":"Pls like and comment ?","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":2,"repostSize":0,"link":"https://ttm.financial/post/189540058","repostId":"1142408805","repostType":4,"repost":{"id":"1142408805","kind":"news","pubTimestamp":1623280126,"share":"https://ttm.financial/m/news/1142408805?lang=en_US&edition=fundamental","pubTime":"2021-06-10 07:08","market":"us","language":"en","title":"U.S. stocks end lower ahead of inflation report","url":"https://stock-news.laohu8.com/highlight/detail?id=1142408805","media":"reuters","summary":"NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants a","content":"<p>NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants awaited inflation data for clues as to when the U.S. Federal Reserve might tighten its dovish monetary policy.</p>\n<p>The retail “meme stock” craze continued unabated.</p>\n<p>All three major U.S. stock indexes reversed earlier gains, but remained range-bound in the absence of any clear market catalysts.</p>\n<p>“There’s a lull period in terms of news,” said Chuck Carlson, chief executive at Horizon Investment Services in Hammond, Indiana. “We’re through earnings period and people are waiting for inflation numbers tomorrow, so you have a mixed market where the major averages aren’t doing much of anything.”</p>\n<p>Heavily shorted meme stocks extended their social media-driven rally, with Aethlon Medical soaring 388.2%.</p>\n<p>Reddit chatter also helped to lift shares of prison operator GEO Group and World Wrestling Entertainment 38.4% and 10.9%, respectively.</p>\n<p>However, other meme stocks such as Clover Health, AMC Entertainment and Bed Bath &amp; Beyond closed lower.</p>\n<p>Retail volume has returned to its January peak, according to Vanda Research, as social media forums scramble to identify the next GameStop Corp, the stock that kicked off the phenomenon.</p>\n<p>“It feels like alternative stock market,” Carlson added. It’s an indication of speculation. You can be successful if you get in at the right moment but it’s very difficult to play successfully over time.”</p>\n<p>“I don’t think you should read too much regarding the broader market.”</p>\n<p>GameStop named Matt Furlong as its new CEO ahead of its earnings report, which showed a quarterly loss of $1.01 per share. Its shares fell over 4% in after-hours trading.</p>\n<p>U.S. President Joe Biden changed course in ongoing negotiations to reach a bipartisan agreement on infrastructure spending after one-on-one talks with Senator Shelley Capito broke down.</p>\n<p>Industrial stocks, which stand to benefit from an infrastructure deal, slid by 1%.</p>\n<p>Washington lawmakers passed a sweeping bill designed to boost the United States’ ability to compete against Chinese technology, providing funds for research and semiconductor production amid an ongoing chip supply drought. The bill now heads to the House of Representatives.</p>\n<p>Even so, the Philadelphia SE Semiconductor index slipped 0.4%.</p>\n<p>The Labor Department’s consumer price index report due out Thursday will provide another take on inflation amid the recovery’s demand/supply imbalance as investors determine whether inflationary pressures, as the Fed asserts, will be transitory.</p>\n<p>The Dow Jones Industrial Average fell 152.68 points, or 0.44%, to 34,447.14; the S&amp;P 500 lost 7.71 points, or 0.18%, at 4,219.55; and the Nasdaq Composite dropped 13.16 points, or 0.09%, to 13,911.75.</p>\n<p>Among the 11 major sectors in the S&amp;P 500, healthcare gained the most.</p>\n<p>Benchmark Treasury yields dropped below 1.5% for the first time since May, weighing on interest-sensitive financials.</p>\n<p>Campbell Soup Co missed quarterly profit expectations and slashed its full-year earnings forecast, sending its shares down 6.5%.</p>\n<p>Drugmaker Merck &amp; Co rose 2.3% on the heels of its announcement the U.S. government had agreed to buy about 1.7 million courses of the company’s experimental COVID-19 treatment, molnupiravir, for about $1.2 billion, if the drug meets regulatory approval.</p>\n<p>Declining issues outnumbered advancers on the NYSE by a 1.12-to-1 ratio; on Nasdaq, a 1.13-to-1 ratio favored decliners.</p>\n<p>The S&amp;P 500 posted 38 new 52-week highs and two new lows; the Nasdaq Composite recorded 126 new highs and 14 new lows.</p>\n<p>Volume on U.S. exchanges was 11.53 billion shares, compared with the 10.74 billion average over the last 20 trading days.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>U.S. stocks end lower ahead of inflation report</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nU.S. stocks end lower ahead of inflation report\n</h2>\n\n<h4 class=\"meta\">\n\n\n2021-06-10 07:08 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://www.reuters.com/article/usa-stocks/us-stocks-u-s-stocks-end-lower-ahead-of-inflation-report-idUSL2N2NR2UG><strong>reuters</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants awaited inflation data for clues as to when the U.S. Federal Reserve might tighten its dovish ...</p>\n\n<a href=\"https://www.reuters.com/article/usa-stocks/us-stocks-u-s-stocks-end-lower-ahead-of-inflation-report-idUSL2N2NR2UG\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"AEMD":"Aethlon Medical Inc",".SPX":"S&P 500 Index",".DJI":"道琼斯",".IXIC":"NASDAQ Composite"},"source_url":"https://www.reuters.com/article/usa-stocks/us-stocks-u-s-stocks-end-lower-ahead-of-inflation-report-idUSL2N2NR2UG","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1142408805","content_text":"NEW YORK (Reuters) - Wall Street ended a see-saw session lower on Wednesday as market participants awaited inflation data for clues as to when the U.S. Federal Reserve might tighten its dovish monetary policy.\nThe retail “meme stock” craze continued unabated.\nAll three major U.S. stock indexes reversed earlier gains, but remained range-bound in the absence of any clear market catalysts.\n“There’s a lull period in terms of news,” said Chuck Carlson, chief executive at Horizon Investment Services in Hammond, Indiana. “We’re through earnings period and people are waiting for inflation numbers tomorrow, so you have a mixed market where the major averages aren’t doing much of anything.”\nHeavily shorted meme stocks extended their social media-driven rally, with Aethlon Medical soaring 388.2%.\nReddit chatter also helped to lift shares of prison operator GEO Group and World Wrestling Entertainment 38.4% and 10.9%, respectively.\nHowever, other meme stocks such as Clover Health, AMC Entertainment and Bed Bath & Beyond closed lower.\nRetail volume has returned to its January peak, according to Vanda Research, as social media forums scramble to identify the next GameStop Corp, the stock that kicked off the phenomenon.\n“It feels like alternative stock market,” Carlson added. It’s an indication of speculation. You can be successful if you get in at the right moment but it’s very difficult to play successfully over time.”\n“I don’t think you should read too much regarding the broader market.”\nGameStop named Matt Furlong as its new CEO ahead of its earnings report, which showed a quarterly loss of $1.01 per share. Its shares fell over 4% in after-hours trading.\nU.S. President Joe Biden changed course in ongoing negotiations to reach a bipartisan agreement on infrastructure spending after one-on-one talks with Senator Shelley Capito broke down.\nIndustrial stocks, which stand to benefit from an infrastructure deal, slid by 1%.\nWashington lawmakers passed a sweeping bill designed to boost the United States’ ability to compete against Chinese technology, providing funds for research and semiconductor production amid an ongoing chip supply drought. The bill now heads to the House of Representatives.\nEven so, the Philadelphia SE Semiconductor index slipped 0.4%.\nThe Labor Department’s consumer price index report due out Thursday will provide another take on inflation amid the recovery’s demand/supply imbalance as investors determine whether inflationary pressures, as the Fed asserts, will be transitory.\nThe Dow Jones Industrial Average fell 152.68 points, or 0.44%, to 34,447.14; the S&P 500 lost 7.71 points, or 0.18%, at 4,219.55; and the Nasdaq Composite dropped 13.16 points, or 0.09%, to 13,911.75.\nAmong the 11 major sectors in the S&P 500, healthcare gained the most.\nBenchmark Treasury yields dropped below 1.5% for the first time since May, weighing on interest-sensitive financials.\nCampbell Soup Co missed quarterly profit expectations and slashed its full-year earnings forecast, sending its shares down 6.5%.\nDrugmaker Merck & Co rose 2.3% on the heels of its announcement the U.S. government had agreed to buy about 1.7 million courses of the company’s experimental COVID-19 treatment, molnupiravir, for about $1.2 billion, if the drug meets regulatory approval.\nDeclining issues outnumbered advancers on the NYSE by a 1.12-to-1 ratio; on Nasdaq, a 1.13-to-1 ratio favored decliners.\nThe S&P 500 posted 38 new 52-week highs and two new lows; the Nasdaq Composite recorded 126 new highs and 14 new lows.\nVolume on U.S. exchanges was 11.53 billion shares, compared with the 10.74 billion average over the last 20 trading days.","news_type":1,"symbols_score_info":{".SPX":0.9,".IXIC":0.9,".DJI":0.9,"AEMD":0.9}},"isVote":1,"tweetType":1,"viewCount":1840,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":187674824,"gmtCreate":1623753904268,"gmtModify":1704210577461,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3579400009595208","authorIdStr":"3579400009595208"},"themes":[],"htmlText":"Like and comment pls","listText":"Like and comment pls","text":"Like and comment pls","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":2,"repostSize":0,"link":"https://ttm.financial/post/187674824","repostId":"1142697857","repostType":4,"isVote":1,"tweetType":1,"viewCount":1292,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":189543286,"gmtCreate":1623283148145,"gmtModify":1704199912054,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3579400009595208","authorIdStr":"3579400009595208"},"themes":[],"htmlText":"??","listText":"??","text":"??","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/189543286","repostId":"2142938243","repostType":4,"isVote":1,"tweetType":1,"viewCount":1043,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":117169226,"gmtCreate":1623123180365,"gmtModify":1704196559664,"author":{"id":"3579400009595208","authorId":"3579400009595208","name":"Ahchiabor","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":12,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3579400009595208","authorIdStr":"3579400009595208"},"themes":[],"htmlText":"Happy to read this news","listText":"Happy to read this news","text":"Happy to read this news","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/117169226","repostId":"2141453253","repostType":4,"repost":{"id":"2141453253","kind":"highlight","weMediaInfo":{"introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"media_name":"Dow Jones","id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"pubTimestamp":1623096780,"share":"https://ttm.financial/m/news/2141453253?lang=en_US&edition=fundamental","pubTime":"2021-06-08 04:13","market":"us","language":"en","title":"Biogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK","url":"https://stock-news.laohu8.com/highlight/detail?id=2141453253","media":"Dow Jones","summary":"Shares rally to second -biggest one-day percentage gain since they went public 30 years agoShares of","content":"<p>Shares rally to second -biggest <a href=\"https://laohu8.com/S/AONE\">one</a>-day percentage gain since they went public 30 years ago</p><p>Shares of Biogen Inc. rocketed to a six-year high in volatile trading Monday, as Wall Street analysts cheered the U.S. Food and Drug Administration's broad labeling that came with the approval of the biotechnology company's Alzheimer's drug.</p><p>The stock <a href=\"https://laohu8.com/S/BIIB\">$(BIIB)$</a> blasted $109.71, or 38.3% higher, to $395.85, the highest close since April 2015. The stock had been halted twice for volatility  during Monday's session, once at 10:44 a.m. Eastern and a second time at 1:37 p.m.</p><p>Trading volume spiked up to 17.7 million shares, compared with the full-day average over the past 30 days of about 1.0 million shares, according to FactSet.</p><p>Earlier Friday, the FDA approved Biogen's Aduhelm , also known as aducanumab, to treat Alzheimer's, the first drug to be approved that promises to actually slow the disease rather than just treat the symptoms.</p><p>Biogen investors were treated to the stock's biggest-ever <a href=\"https://laohu8.com/S/AONE.U\">one</a>-day price gain, and second-biggest one-day percentage gain since it went public in September 1991. The stock had shot up $108.62, or 44.0%, on Nov. 4, 2020, after the FDA said there was \"substantial evidence\"</p><p>\"Currently available options only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer's,\" said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research. \"As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research an innovation.\"</p><p>As the FDA described, accelerated approval can be based on the drug's effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients, with \"a required post-approval trial\" to verify the drug provides that expected clinical benefit.</p><p>Bernstein analyst Aaron Gal said approval under accelerated pathway is a distinction without a difference. \"The pathway allows for approval based on surrogate market, rather than completed efficacy endpoint data,\" Gal wrote in a note to clients. \"As long as Biogen does not challenge the use of the path, which they obviously would not, the approval holds.\"</p><p>Evercore ISI's Umer Raffat noted that the option of Accelerated Approval was not discussed by the FDA's advisory committee. And as the drug has \"clearly shown\" in all trials to substantially reduce amyloid beta plaques, the \"reduction in plaques is reasonably likely to result in clinical benefit.\"</p><p>Regarding labeling, Bernstein's Gal said it is \"almost shockingly broad,\" as the label just said Aduhelm is indicated for the treatment of Alzheimer's disease.</p><p>\"Thus, the approved population is broader than the tested population (mild-moderate Alzheimer's patients),\" Gal wrote. \"There is also no restriction on treatment duration suggesting that patients can stay on treatment until either all plaque is removed or the patient progresses.\"</p><p>Evercore's Raffat concurred, saying the label reads very very broad. He indicated that investors could be relieved, as there was some concern that the target population might be limited, and/or require very frequent monitoring.</p><p>Although pricing is still unknown, the Institute of Clinical and Economic Review (ICER) said that due to the relatively small overall health gains demonstrated in Phase 3 clinical trials, the drug should be price no higher than $8,400 a year, as MarketWatch's Jaimy Lee reported .</p><p>Some analysts say Biogen could price the drug higher than that, even though that might potentially trigger a regulatory response.</p><p>Evercore's Raffat said his financial estimates on Biogen include an estimate of $10,000, while Bernstein's Gal said the pricing could end up \"much higher,\" possibly as high as more than $30,000.</p><p>Gal said Biogen has a long history of pricing drugs in the \"specialty\" range, and is less likely to fear a backlash. \"Biogen would justify the price by arguing the total system impact would be modest upfront and that it will use the money to provide substantial services to [Alzheimer's disease] patients,\" Gal wrote.</p><p>Biogen and Eisai Inc., the U.S. subsidiary of Japan-based Eisai Co. Ltd. (4523.TO), announced after Aduhelm's approval programs intended to support access for all qualified patients, including those from traditionally underserved populations.</p><p>Eisai's U.S.-listed shares skyrocketed 68.9% in afternoon trading, on track for a record close and the biggest one-day gain since it started trading in the U.S. in December 1995.</p><p>\"We are committed to access and health equity as top priorities and will continue working with multiple stakeholders with the goal of helping patients who may benefit from treatment obtain care as quickly as possible,\" said Alisha Alaimo, president of Biogen U.S.</p><p>Biogen's stock has now run up 61.7% year to date, while SPDR Health Care Select Sector exchange-traded fund <a href=\"https://laohu8.com/S/XLV\">$(XLV)$</a> has gained 8.0% and the S&amp;P 500 index  has advanced 12.5%.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Biogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nBiogen stock rockets to 6-year high after Alzheimer's drug gets FDA OK\n</h2>\n\n<h4 class=\"meta\">\n\n\n<div class=\"head\" \">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Dow Jones </p>\n<p class=\"h-time\">2021-06-08 04:13</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<p>Shares rally to second -biggest <a href=\"https://laohu8.com/S/AONE\">one</a>-day percentage gain since they went public 30 years ago</p><p>Shares of Biogen Inc. rocketed to a six-year high in volatile trading Monday, as Wall Street analysts cheered the U.S. Food and Drug Administration's broad labeling that came with the approval of the biotechnology company's Alzheimer's drug.</p><p>The stock <a href=\"https://laohu8.com/S/BIIB\">$(BIIB)$</a> blasted $109.71, or 38.3% higher, to $395.85, the highest close since April 2015. The stock had been halted twice for volatility  during Monday's session, once at 10:44 a.m. Eastern and a second time at 1:37 p.m.</p><p>Trading volume spiked up to 17.7 million shares, compared with the full-day average over the past 30 days of about 1.0 million shares, according to FactSet.</p><p>Earlier Friday, the FDA approved Biogen's Aduhelm , also known as aducanumab, to treat Alzheimer's, the first drug to be approved that promises to actually slow the disease rather than just treat the symptoms.</p><p>Biogen investors were treated to the stock's biggest-ever <a href=\"https://laohu8.com/S/AONE.U\">one</a>-day price gain, and second-biggest one-day percentage gain since it went public in September 1991. The stock had shot up $108.62, or 44.0%, on Nov. 4, 2020, after the FDA said there was \"substantial evidence\"</p><p>\"Currently available options only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer's,\" said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research. \"As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research an innovation.\"</p><p>As the FDA described, accelerated approval can be based on the drug's effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients, with \"a required post-approval trial\" to verify the drug provides that expected clinical benefit.</p><p>Bernstein analyst Aaron Gal said approval under accelerated pathway is a distinction without a difference. \"The pathway allows for approval based on surrogate market, rather than completed efficacy endpoint data,\" Gal wrote in a note to clients. \"As long as Biogen does not challenge the use of the path, which they obviously would not, the approval holds.\"</p><p>Evercore ISI's Umer Raffat noted that the option of Accelerated Approval was not discussed by the FDA's advisory committee. And as the drug has \"clearly shown\" in all trials to substantially reduce amyloid beta plaques, the \"reduction in plaques is reasonably likely to result in clinical benefit.\"</p><p>Regarding labeling, Bernstein's Gal said it is \"almost shockingly broad,\" as the label just said Aduhelm is indicated for the treatment of Alzheimer's disease.</p><p>\"Thus, the approved population is broader than the tested population (mild-moderate Alzheimer's patients),\" Gal wrote. \"There is also no restriction on treatment duration suggesting that patients can stay on treatment until either all plaque is removed or the patient progresses.\"</p><p>Evercore's Raffat concurred, saying the label reads very very broad. He indicated that investors could be relieved, as there was some concern that the target population might be limited, and/or require very frequent monitoring.</p><p>Although pricing is still unknown, the Institute of Clinical and Economic Review (ICER) said that due to the relatively small overall health gains demonstrated in Phase 3 clinical trials, the drug should be price no higher than $8,400 a year, as MarketWatch's Jaimy Lee reported .</p><p>Some analysts say Biogen could price the drug higher than that, even though that might potentially trigger a regulatory response.</p><p>Evercore's Raffat said his financial estimates on Biogen include an estimate of $10,000, while Bernstein's Gal said the pricing could end up \"much higher,\" possibly as high as more than $30,000.</p><p>Gal said Biogen has a long history of pricing drugs in the \"specialty\" range, and is less likely to fear a backlash. \"Biogen would justify the price by arguing the total system impact would be modest upfront and that it will use the money to provide substantial services to [Alzheimer's disease] patients,\" Gal wrote.</p><p>Biogen and Eisai Inc., the U.S. subsidiary of Japan-based Eisai Co. Ltd. (4523.TO), announced after Aduhelm's approval programs intended to support access for all qualified patients, including those from traditionally underserved populations.</p><p>Eisai's U.S.-listed shares skyrocketed 68.9% in afternoon trading, on track for a record close and the biggest one-day gain since it started trading in the U.S. in December 1995.</p><p>\"We are committed to access and health equity as top priorities and will continue working with multiple stakeholders with the goal of helping patients who may benefit from treatment obtain care as quickly as possible,\" said Alisha Alaimo, president of Biogen U.S.</p><p>Biogen's stock has now run up 61.7% year to date, while SPDR Health Care Select Sector exchange-traded fund <a href=\"https://laohu8.com/S/XLV\">$(XLV)$</a> has gained 8.0% and the S&amp;P 500 index  has advanced 12.5%.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"BIIB":"渤健公司"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2141453253","content_text":"Shares rally to second -biggest one-day percentage gain since they went public 30 years agoShares of Biogen Inc. rocketed to a six-year high in volatile trading Monday, as Wall Street analysts cheered the U.S. Food and Drug Administration's broad labeling that came with the approval of the biotechnology company's Alzheimer's drug.The stock $(BIIB)$ blasted $109.71, or 38.3% higher, to $395.85, the highest close since April 2015. The stock had been halted twice for volatility  during Monday's session, once at 10:44 a.m. Eastern and a second time at 1:37 p.m.Trading volume spiked up to 17.7 million shares, compared with the full-day average over the past 30 days of about 1.0 million shares, according to FactSet.Earlier Friday, the FDA approved Biogen's Aduhelm , also known as aducanumab, to treat Alzheimer's, the first drug to be approved that promises to actually slow the disease rather than just treat the symptoms.Biogen investors were treated to the stock's biggest-ever one-day price gain, and second-biggest one-day percentage gain since it went public in September 1991. The stock had shot up $108.62, or 44.0%, on Nov. 4, 2020, after the FDA said there was \"substantial evidence\"\"Currently available options only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer's,\" said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research. \"As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research an innovation.\"As the FDA described, accelerated approval can be based on the drug's effect on a surrogate endpoint that is reasonably likely to predict a clinical benefit to patients, with \"a required post-approval trial\" to verify the drug provides that expected clinical benefit.Bernstein analyst Aaron Gal said approval under accelerated pathway is a distinction without a difference. \"The pathway allows for approval based on surrogate market, rather than completed efficacy endpoint data,\" Gal wrote in a note to clients. \"As long as Biogen does not challenge the use of the path, which they obviously would not, the approval holds.\"Evercore ISI's Umer Raffat noted that the option of Accelerated Approval was not discussed by the FDA's advisory committee. And as the drug has \"clearly shown\" in all trials to substantially reduce amyloid beta plaques, the \"reduction in plaques is reasonably likely to result in clinical benefit.\"Regarding labeling, Bernstein's Gal said it is \"almost shockingly broad,\" as the label just said Aduhelm is indicated for the treatment of Alzheimer's disease.\"Thus, the approved population is broader than the tested population (mild-moderate Alzheimer's patients),\" Gal wrote. \"There is also no restriction on treatment duration suggesting that patients can stay on treatment until either all plaque is removed or the patient progresses.\"Evercore's Raffat concurred, saying the label reads very very broad. He indicated that investors could be relieved, as there was some concern that the target population might be limited, and/or require very frequent monitoring.Although pricing is still unknown, the Institute of Clinical and Economic Review (ICER) said that due to the relatively small overall health gains demonstrated in Phase 3 clinical trials, the drug should be price no higher than $8,400 a year, as MarketWatch's Jaimy Lee reported .Some analysts say Biogen could price the drug higher than that, even though that might potentially trigger a regulatory response.Evercore's Raffat said his financial estimates on Biogen include an estimate of $10,000, while Bernstein's Gal said the pricing could end up \"much higher,\" possibly as high as more than $30,000.Gal said Biogen has a long history of pricing drugs in the \"specialty\" range, and is less likely to fear a backlash. \"Biogen would justify the price by arguing the total system impact would be modest upfront and that it will use the money to provide substantial services to [Alzheimer's disease] patients,\" Gal wrote.Biogen and Eisai Inc., the U.S. subsidiary of Japan-based Eisai Co. Ltd. (4523.TO), announced after Aduhelm's approval programs intended to support access for all qualified patients, including those from traditionally underserved populations.Eisai's U.S.-listed shares skyrocketed 68.9% in afternoon trading, on track for a record close and the biggest one-day gain since it started trading in the U.S. in December 1995.\"We are committed to access and health equity as top priorities and will continue working with multiple stakeholders with the goal of helping patients who may benefit from treatment obtain care as quickly as possible,\" said Alisha Alaimo, president of Biogen U.S.Biogen's stock has now run up 61.7% year to date, while SPDR Health Care Select Sector exchange-traded fund $(XLV)$ has gained 8.0% and the S&P 500 index  has advanced 12.5%.","news_type":1,"symbols_score_info":{"ESALY":0.9,"BIIB":0.9}},"isVote":1,"tweetType":1,"viewCount":1263,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"lives":[]}