Illumina's stock experienced a significant after-hours plunge of 5.70% following the release of its fourth-quarter and fiscal year 2025 financial results.
The company reported Q4 non-GAAP earnings of $1.35 per diluted share, beating the FactSet consensus estimate of $1.24. Revenue for the quarter also exceeded expectations, coming in at $1.16 billion compared to the estimated $1.12 billion.
Despite these positive results, investors reacted negatively to the company's fiscal 2026 outlook. Illumina provided guidance for non-GAAP diluted EPS in the range of $5.05 to $5.20, which straddles the consensus estimate of $5.06. While revenue guidance of $4.5 billion to $4.6 billion exceeds the $4.41 billion consensus, the mixed EPS outlook appears to have driven the after-hours selloff.
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